Which of the following is a common proton pump inhibitor (PPI)?

Lansoprazole is a well-known proton pump inhibitor (PPI) that works by irreversibly inhibiting the hydrogen-potassium ATPase enzyme system in the gastric parietal cells, leading to a decrease in gastric acid secretion. PPIs are commonly used to treat conditions associated with excess gastric acid, such as gastroesophageal reflux disease (GERD) and peptic ulcers. Lansoprazole is part of a class of medications that effectively reduce stomach acid production and provide relief from symptoms associated with acid-related disorders.

In contrast, famotidine and ranitidine are both histamine-2 receptor antagonists (H2 blockers), which function by blocking histamine from triggering acid secretion. Metoclopramide is a prokinetic agent that increases the movement of the stomach and intestines but is not classified as a PPI. This distinction is essential in understanding their mechanisms of action and therapeutic uses in treating gastrointestinal conditions.